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The correlation between high testosterone and high zinc levels is apparent in many studies ( 15 ) ( 16 ) ( 17 )( 18 ) but not in older African- American men. We used data from the second wave of the National Health and Nutrition Examination Survey among older adults (21–75 years), who were more likely to be Black than white ( 19 ). Exports of white and other non- Black items from the survey were coded with respect to race. We also used data on testosterone at baseline (19,20) to evaluate the effect of testosterone treatment and the age at testosterone peak and trough in African-American men. All analyses were performed in SAS software, version 9.2 (SAS Institute, Cary, North Carolina). In the first wave of the survey (1999–2002) there were 903 Black or African-American men from this age range. Participants were asked whether they consumed or had consumed any alcohol, smoked any cigarettes during the preceding four weeks, or had ever used any hormonal agents or drugs in the past four weeks (n = 1,004). Alcohol consumption (including tea, wine, beer, spirits and all other alcoholic beverages) was considered by the men to have occurred in the current week (n = 1,038) and the days before (n = 636). Cigarette smoking was defined as any use in a single week (n = 1,051) ( 19 ). None of the participants reported taking antidepressants or other psychiatric drugs during the preceding four weeks; any use was defined (n = 1,052) as "other" rather than "drug" on this questionnaire. There were 2,600 men aged 40–59 years (5.7 %) who had had contact with an STD clinic in the preceding month in the United States. We asked about these men's characteristics, and their ages at last known contact with the clinic were recorded. These men included women only, and men and women were considered the same person within the study population. DISCUSSION During the past 10 years, the prevalence of prevalent HIV infections has increased dramatically in the United States (21) (21–24). Despite evidence to the contrary—such as findings from the Women's Health Initiative (25) and other studies (26) (27,28)—the prevalence of heterosexual HIV infections has remained stable; however, the number of new HIV infections reported from 2005 to 2010 (29) has increased by more than 40 %. A number of hypotheses that are proposed to explain the increasing levels of HIV infection have been proposed; however, none of these hypotheses have been tested empir Similar articles: